Publications

  1. Sin JH, Zuckerman C, Cortez JT, Eckalbar W, Erle DJ, Anderson MS, Waterfield MR. The epigenetic regulator ATF7ip inhibits IL-2 expression regulating Th17 responses. J Exp Med. 2019. In Press.
  2. Tsui JL, Estrada OA, Deng Z, Wang KM, Law CS, Elicker BM, Jones KD, Dell SD, Gudmundsson G, Hansdottir S, Helfgott SM, Volpi S, Gattorno M, Waterfield MR, Chan AY, Chung SA, Ley B, Shum AK. Analysis of pulmonary features and treatment approaches in the COPA syndrome. ERJ Open Res. 2018 Apr; 4(2).
  3. LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS. Identification of a novel cis-regulatory element essential for immune tolerance. J Exp Med. 2015 Nov 16; 212(12):1993-2002.
  4. Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015 Jun; 47(6):654-60.
  5. Waterfield M, Khan IS, Cortez JT, Fan U, Metzger T, Greer A, Fasano K, Martinez-Llordella M, Pollack JL, Erle DJ, Su M, Anderson MS. The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014 Mar; 15(3):258-65.
  6. Waterfield M, Anderson MS. Autoimmunity's collateral damage: Immunodeficiency hints at autoreactivity to cytokines. Nat Med. 2011 Sep 07; 17(9):1054-5.
  7. Waterfield M, Anderson MS. Clues to immune tolerance: the monogenic autoimmune syndromes. Ann N Y Acad Sci. 2010 Dec; 1214:138-55.
  8. Babu GR, Waterfield M, Chang M, Wu X, Sun SC. (2006) Deregulated Activation of Oncoprotein Kinase Tpl2/Cot in HTLV-I-Transformed T cells. Journal of Biological Chemistry 281(20),14041-7.
  9. Babu GR, Jin W, Norman L, Waterfield M, Chang M, Wu X, Zhang M, Sun SC. (2006) Phosphorylation of NF-kb1/p105 by the Oncoprotein Kinase Tpl2: Implications for a Novel Mechanism of Tpl2 Regulation. Biochim Biophys Acta 1763(2), 174-81.
  10. Geskey J, Waterfield M, Weber H, Graf G. (2005) Pulmonary AVM: An Unexplained Case of Hypoxemia. Clinical Pediatrics 44(3), 263-66.
  11. Waterfield MR, Zhang M, Norman LP, Sun SC. NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase. Mol Cell. 2003 Mar; 11(3):685-94.
  12. Waterfield M, Jin W, Reiley W, Zhang M, Sun SC. (2004) IkB Kinase is an Essential Component of the Tpl2 Signaling Pathway. Molecular and Cellular Biology 24(13), 6040-48.
  13. Xiao G, Cvijic ME, Fong A, Harhaj E, Uhlik M, Waterfield M, Sun SC. (2001) Retroviral Oncoprotein Tax Induces Processing of NF-kB2/p100 in T cells: Evidence for Involvement of IKKa. EMBO Journal 20, 6805-15.
  14. Rivera-Walsh I, Waterfield M, Xiao G, Fong A, Sun SC. (2001) NF-kB Signaling Pathway Governs Trail Gene Expression and Human T-cell Leukemia Tax-induced T-cell Death. Journal of Biological Chemistry 276, 40385-88.